While building my 320-palace city, I was perplexed. 1 large palace in each set of 80, in the same relative position all 4 times, required more desirability than it should have to evolve (or to not devolve once it had evolved to a luxury palace). It wasn't just that the most desirable tile needed to be slightly more desirable--whether the large palace evolved sometimes depended on where the extra desirability booster was built. I eventually came up with a theory to explain the observations.
It appears to me that for a 4x4 house, the desirability of the ENE edge tile (the one adjacent to and NW of the E tile) is ignored. In other words, contrary to "common knowledge", the most desirable tile of a 4x4 house does not determine evolution and devolution if that tile is the ENE edge tile. (It is possible that the desirability of some other tiles may also be ignored.)
I don't intend to investigate this further, but if someone else does I'd like to see the results.
It appears to me that for a 4x4 house, the desirability of the ENE edge tile (the one adjacent to and NW of the E tile) is ignored. In other words, contrary to "common knowledge", the most desirable tile of a 4x4 house does not determine evolution and devolution if that tile is the ENE edge tile. (It is possible that the desirability of some other tiles may also be ignored.)
I don't intend to investigate this further, but if someone else does I'd like to see the results.